Health Benefits of Polyphenol Hydroxytyrosol from Olive Leaf
Olea25® 25% Hydroxytyrosol, a polyphenol extracted from Olive Leaf. The Health Benefits of Hydroxytyrosol and the Polyphenols extracted from Olive Leaf have antioxidant and anti-inflammatory properties that support mitochondria function.
Antioxidant Benefits of Hydroxytyrosol
Hydroxytyrosol- Strongest in vitro antioxidant potential among all olive polyphenols.
Hydroxytyrosol reduced lipid peroxidation and other markers of oxidative stress. Hydroxytyrosol has a protective role on Human melanoma cells exposed to UV-B radiation
Anti-Inflammatory Benefits of Hydroxytyrosol
Hydroxytyrosol reduces acute and chronic inflammatory biomarkers. The biomarkers are found in the disease process of osteoarthritis, metabolic syndrome, heart disease and cancer.
Hydroxytyrosol may represent a natural agent for the control of inflammatory genes.
Naunyn Schmiedebergs Archives of Pharmacology. 2005 June;371(6):457-65
Mitochondrial Benefits of Hydroxytyrosol
Providing the mitochondria with nutrients, such as the plant-based polyphenol Hydroxytyrosol(HT) and the Mediterranean Diet, can improve mitochondrial function and stimulate mitochondrial biogenesis.
Promoting these cellular and energy systems can positively impact the diseased processes of cancer, cardiovascular disease, obesity and diabetes.
Mitochondrial function was found to:
- Increase in activity and protein expression
- Increase oxygen consumption
- Decrease fatty acid content in fat cells
Hydroxytyrosol(HT) has been implicated in the ability to reduce Reaction Oxygen Species(ROS) and stimulate the Phase II antioxidant system.
Furhtermore, HT with the ability to induce mitochondrial biogenesis and express SIRT-1 that increases lipolysis. This would result in a reduction in the accumulation of fat.
The more fat there is, the more inflammation it creates.
This suggests the influence of HT on mitochondrial function and mitochondrial biogenesis.
Mitochondrial nutrients, such as Hydroxytyrosol, stimulate mitochondrial function and biogenesis, and prevent diabetes and obesity-related mitochondrial dysfunction, thus reducing the risk of cardiovascular disease.